Macro
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month values ▾
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|
| +0.30 | +0.20 | +0.20 | +0.09 | +0.20 | +0.20 | +0.20 | +0.20 | -0.12 | +0.10 | +0.10 | +0.10 |
Money rotated out of 'old economy' pharma into internet stocks, leaving my franchise neglected and flat, while drug-pricing politics began resurfacing ahead of the 2000 election even as genomics excitement built.
How this mood is scored ▾
Astra AB and Zeneca Group PLC completed their $37 billion merger, forming AstraZeneca PLC, with operations in over 100 countries and a strong US presence. The integration process began immediately, supported by a unified brand identity and new corporate logo. As a leading pharmaceutical firm, AstraZeneca focuses on key therapeutic areas including oncology, cardiovascular, and respiratory products, positioning it for significant market influence.
Jesse Gelsinger, an 18-year-old with OTC deficiency, died in 1999 from a severe immune reaction to an adenovirus-based gene therapy trial at the University of Pennsylvania. The incident exposed ethical lapses, including undisclosed risks and investigator conflicts of interest, triggering FDA investigations, trial halts, and stricter clinical oversight. The tragedy led to a prolonged stall in gene therapy funding and development, though the field eventually rebounded with advances in vector safety and CRISPR technology.