Macro
Search catalysts, news stories, and pressures, or browse the trust-weighted news feed below.
month values ▾
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|
| +0.40 | +0.40 | +0.40 | +0.40 | +0.40 | +0.14 | +0.40 | +0.17 | +0.40 | +0.30 | +0.30 | +0.20 |
Vaccine revenue was a tens-of-billions windfall and reopening restored elective procedures, driving big-pharma and vaccine makers to peaks by late summer; but rising rates began mauling unprofitable small-cap biotech into year end.
How this mood is scored ▾
The FDA approved Biogen and Eisai's Aduhelm under accelerated pathways despite advisory panel objections over inconclusive evidence of clinical benefit. The drug targets amyloid plaques in Alzheimer's patients but requires further trials to confirm efficacy, raising concerns over cost, patient access, and Medicare impact. Biogen's stock surged 39% following the announcement, reflecting market optimism amid controversy.
The FDA granted full approval to Pfizer and BioNTech's COVID-19 vaccine, enhancing confidence in vaccine mandates by businesses, schools, and the military. The move allows Pfizer and BioNTech to market the vaccine directly and potentially increase pricing, with broader implications for vaccination rates and public health policy. The vaccine, now branded as Comirnaty, demonstrated 91% efficacy and met rigorous safety and manufacturing standards.